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Link Found Between Eye Disease and Alzheimer’s

By David Blyweiss, M.D., Advanced Natural Wellness

September 7, 2018

  • Can your eye health predict Alzheimer’s?
  • Eat to protect your vision… and your memories
  • Supplements for your eyesight and brainpower

The thought of losing your vision is a scary idea. Still, I find that many of my patients don’t actively start taking care of their eyes until they start experiencing problems.

By that time it is often too late resolve many of the most common eye disorders associated with aging. This is particularly true when it comes to the three that are most devastating.

These diseases alone are pretty frightening. But what I’m going to share with you next is absolutely terrifying. People with these vision-destroying conditions have a 45 to 50 percent greater risk of Alzheimer’s disease compared to people without them! I’m talking about macular degeneration, glaucoma and diabetic retinopathy.

The connection between eye disease and Alzheimer’s isn’t a stretch, by any means. You see, the retina is actually an extension of the brain and central nervous system. At the same time conditions such as AMD, glaucoma and diabetic retinopathy are, in part, considered to be neurodegenerative.

With this in mind, it is suspected that retinal neuron damage associated with these eye disorders triggers the spread of disease to structures of the brain. And the reverse can happen, too – where degeneration of the brain moves into the retina.

This means that if you want to dodge Alzheimer’s it’s important to not only control what happens in your brain, but also what happens to your eyes.

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A thorough opthalmalogic examination can pick up the earliest signs of amyloid plaquing in the retinal vasculature and structural components.(***, ****) It  “provides an opportunity to use a minimally invasive approach to examine the pathological features in the brain – through the transparent medium of the eye.”(*****)

Eat to Protect Your Vision… and Your Memories

There is one dietary pattern that has been shown over and over again to protect your vision. It also works exceedingly well to keep your brain sharp and preserve your memories.

I’m talking about a Mediterranean style diet.

  • Eating like a Mediterranean can cut your risk of AMD by more than a third. The abundance of antioxidant-rich fruits and vegetables that come with his way of eating are one part of the reason it’s so protective for your eyes. They’re loaded with vitamins A, C and E, along with protective carotenoids like lutein and zeaxanthin.
  • A Mediterranean style diet rich in nuts and extra virgin olive oil reduces the relative risk of diabetic retinopathy by a significant 43%. It is also one of the best diets for glycemic control and cardiovascular risk factors associated with diabetes.
  • People who eat more fruits, vegetables (especially dark leafy greens) and omega-3 rich fish, which are all part of the Mediterranean dietary pattern, have lower chances of developing glaucoma. Some evidence even suggests that olive oil can reduce the intraocular pressure associated with glaucoma.
  • Here’s the best news of all. Those who stick most closely with the Mediterranean way of eating have brains that appear to be about five years younger than they really are. Just think about that for a minute. You can actually shave five years off of your brain’s age!
  • Additionally, those who eat like a Mediterranean have significantly fewer beta-amyloid deposits than those who eat standard American fare. In fact, this way of eating could reduce your chances of cognitive impairment and Alzheimer’s by about 33%.

Taken all together, this makes a Mediterranean style diet a perfect way to protect your precious vision and memories

Supplements for Your Eyesight and Brainpower

There are also a few eye-supporting supplements you can take, just to be on the safe side.

I recommend a top-quality eye formula that contains lutein and zeaxanthin as the lead ingredients. These nutrients aren’t just good for the eyes. As it turns out, patients with Alzheimer’s disease are shown to be deficient in these two carotenoids. But people who supplement with them are able to boost their cognitive abilities.

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You also want to make sure the formula includes other eye and brain-supporting nutrients like omega-3 fatty acids, zinc, and vitamins A, C and E.

Remember, your eyes are your key to independence. They may even be the keeper of your memories. Start safeguarding them now so that you can maintain your freedom, mental acuity and daily activities for years to come.

SOURCES:

Eye conditions provide new lens for screening for Alzheimer’s. News Release. University of Washington. Aug 2018.

Lee CS, et al. Associations between recent and established ophthalmic conditions and risk of Alzheimer’s disease. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. 2018. Epub ahead of print.

London A, et al. The retina as a window to the brain-from eye research to CNS disorders. Nat Rev Neurol. 2013 Jan;9(1):44-53.

Yücel Y, et al. Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration. Prog Brain Res. 2008;173:465-78.

Gupta N, et al. What changes can we expect in the brain of glaucoma patients? Surv Ophthalmol. 2007 Nov;52 Suppl 2:S122-6.

Fruit-Rich Mediterranean Diet with Antioxidants May Cut AMD Risk by More than a Third. News Release. American Academy of Ophthalmology. Oct 2016.

Díaz-López A, et al. Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial. Diabetes Care. 2015 Nov;38(11):2134-41.

Esposito K, et al. A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses. BMJ Open. 2015; 5(8): e008222.

Owaifeer AM, et al. The Role of Diet in Glaucoma: A Review of the Current Evidence. Ophthalmol Ther. 2018 Jun; 7(1): 19–31.

Simsek T, et al. Prevention of intraocular pressure elevation with oleuropein rich diet in rabbits, during the general anaesthesia. Springerplus. 2016; 5(1): 952.

Gu Y, et al. Mediterranean diet and brain structure in a multiethnic elderly cohort. Neurology. 2015 Nov 17;85(20):1744-51.

Berti V, et al. Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults. Neurology Apr 2018, 10.1212/WNL.0000000000005527

Singh B, et al. Association of mediterranean diet with mild cognitive impairment and Alzheimer’s disease: a systematic review and meta-analysis. J Alzheimers Dis. 2014;39(2):271-82.

Cho KS, et al. Recent Advances in Studies on the Therapeutic Potential of Dietary Carotenoids in Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity, vol. 2018, Article ID 4120458, 13 pages, 2018.

Hammond BR, et al. Effects of Lutein/Zeaxanthin Supplementation on the Cognitive Function of Community Dwelling Older Adults: A Randomized, Double-Masked, Placebo-Controlled Trial. Front Aging Neurosci. 2017; 9: 254.

*** Transl Psychiatry. 2013 Feb; 3(2): e233. Retinal vascular biomarkers for early detection and monitoring of Alzheimer’s disease. S Frost,1,2,3 Y Kanagasingam,1,2 H Sohrabi,4 J Vignarajan,1,2 P Bourgeat,1,5 O Salvado,1,5 V Villemagne,5,6,7C C Rowe,6 S Lance Macaulay,8 C Szoeke,8,9 K A Ellis,7,9,10 D Ames,9,10 C L Masters,7 S Rainey-Smith,4R N Martins,4,*

****Alzheimer’s Research & Therapy 2017 9:13. Retinal vascular and structural changes are associated with amyloid burden in the elderly; opthalmic biomarkers of preclinical Alzheimer’s disease.

  • Mojtaba Golzan author,
  • Kathryn Goozee,
  • Dana Georgevsky,
  • Alberto Avolio,
  • Pratishtha Chatterjee,
  • Kaikai Shen,
  • Vivek Gupta,
  • Roger Chung,
  • Greg Savage,
  • Carolyn F. Orr,
  • Ralph N. Martinsand
  • Stuart L. Graham

*****Front Neurol. 2016; 7: 55. Visual and Ocular Manifestations of Alzheimer’s Disease and Their Use as Biomarkers for Diagnosis and Progression. Fatimah Zara Javaid,1 Jonathan Brenton,1 Li Guo,1 and Maria F. Cordeiro1,2,